1998 Internat J Legal Med: Alele frequency distributions of the polymorphic STR loci HUMVWA, HUMFES, HUMF13A01 and the VNTR D1S80 in a Filipino population from Metro Manila
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Alele frequency distributions of the polymorphic STR loci HUMVWA, HUMFES,
HUMF13A01 and the VNTR D1S80 in a Filipino population from Metro Manila
S. C. Halos (1)(2), E. S. Fortuno III (2), A. C. M. Ferreon (1), J. Y Chu (2), J. Miranda (1), S. Harada (3), M. Benecke (1)(4)
[Photos here (DNA team / UP Diliman 1997)]
Published in Internat J Legal Med 1998;111(4):224-6
Scientists: This is a raw version - please order the original at your library, or get the .pdf file here.
(1) Molecular Biology & Biotechnology Program, Albert Hall, University of the Philippines, Diliman 1101 Quezon City, Metro Manila, Philippines
(2) DNA Analysis Laboratory, Natural Sciences Research Institute, University of the Philippines, Diliman 1101 Quezon City, Metro Manila, Philippines
(3) Department of Forensic Medicine, Tsukuba University, Tsukuba, Japan
(4) Institute for Legal Medicine, University of Cologne, Melatengürtel 60-62, D-50823 Köln, Germany (not valid anymore, see very bottom)
(5) e-mail: benecke@uni-koeln.de (not valid anymore, see very bottom)
Received: 7 July 1997 / Received in revised form: 18 September 1997
Abstract Allele frequency distributions at the short tandem repeat (STR) loci HUMVWA, HUMFES, HUMF13A01 and of the variable number of tandem
repeat (VNTR) locus D1S80 were determined in a Filipino population from Metro Manila (103 individuals) by use of the polymerase chain reaction
(PCR) followed by polyacrylamide gel electrophoresis (PAGE). The exact test demonstrated that all four loci had no deviations from Hardy-Weinberg
equilibrium (HWE) with the only reservation that the exact test p-value for F13A01 is weak. The discriminating power is 0.82 for D1S80, and the
expected exclusion chance is 0.85 for F13A01, 0.83 for FES, and 0.93 for VWA. The observed heterozygosity rates are 0.63 for D1S80, 0.66 for
F13A01, 0.67 for FES, and 0.80 for VWA. The exact test for independance between all loci gave a p-value of 0.0195. This is the first time that Filipino
population data of DNA loci of forensic importance are reported.
Key words Population study - HUMFES - HUMVWA - HUMF13A01 - D1S80 - Philippines
More of MB´s DNA typing articles (including more Filipino articles!).
Mark Benecke, Ph.D., Certified & Sworn In Forensic Biologist, International Forensic Research & Consulting, Postfach 250411, 50520 Cologne, Germany; E-Mail: forensic@benecke.com, www.benecke.com, Emergency Text / SMS for crime cases only +49-173-287-3136. Absolutely no social networks & newsletters. Never send .doc, .ppt, .xml -- .rtf and .pdf only. Tx!
(1) Molecular Biology & Biotechnology Program, Albert Hall, University of the Philippines, Diliman 1101 Quezon City, Metro Manila, Philippines
(2) DNA Analysis Laboratory, Natural Sciences Research Institute, University of the Philippines, Diliman 1101 Quezon City, Metro Manila, Philippines
(3) Department of Forensic Medicine, Tsukuba University, Tsukuba, Japan
(4) Institute for Legal Medicine, University of Cologne, Melatengürtel 60-62, D-50823 Köln, Germany (not valid anymore, see very bottom)
(5) e-mail: benecke@uni-koeln.de (not valid anymore, see very bottom)
Received: 7 July 1997 / Received in revised form: 18 September 1997
Abstract Allele frequency distributions at the short tandem repeat (STR) loci HUMVWA, HUMFES, HUMF13A01 and of the variable number of tandem
repeat (VNTR) locus D1S80 were determined in a Filipino population from Metro Manila (103 individuals) by use of the polymerase chain reaction
(PCR) followed by polyacrylamide gel electrophoresis (PAGE). The exact test demonstrated that all four loci had no deviations from Hardy-Weinberg
equilibrium (HWE) with the only reservation that the exact test p-value for F13A01 is weak. The discriminating power is 0.82 for D1S80, and the
expected exclusion chance is 0.85 for F13A01, 0.83 for FES, and 0.93 for VWA. The observed heterozygosity rates are 0.63 for D1S80, 0.66 for
F13A01, 0.67 for FES, and 0.80 for VWA. The exact test for independance between all loci gave a p-value of 0.0195. This is the first time that Filipino
population data of DNA loci of forensic importance are reported.
Key words Population study - HUMFES - HUMVWA - HUMF13A01 - D1S80 - Philippines
More of MB´s DNA typing articles (including more Filipino articles!).
